Potential Use Cases

Primary care line leaders

  1. Facilitate clinician scientists’ research around hereditary diseases.
  2. Facilitate automation of screening family health history for other common, inherited conditions for which there are recommended management changes (e.g. familial hypercholesterolemia).
  3. Identify individuals who meet National Comprehensive Cancer Center (NCCN) criteria for genetic testing enterprise-wide. Characterize the cohort.
  4. Facilitate pre-test genetics education and request of genetic testing.
  5. Facilitate cascade genetic testing.
  6. Collect targeted family history to determine genetic test eligibility.
  7. Return negative genetic test results to patients with chatbot.

Healthcare system leaders

  1. Configure automation to address straightforward patient care issues and allow staff with relevant expertise to focus care on complex cases.
  2. Facilitate clinician scientists’ research around hereditary diseases.
  3. Facilitate automation of screening family health history for other common, inherited conditions.
  4. Population Analytics
    1. Identify individuals who meet National Comprehensive Cancer Center (NCCN) criteria for genetic testing enterprise-wide. Characterize the cohort.
    2. Identify individuals who meet NCCN criteria for genetic testing that are part of a pre-identified cohort (i.e., validate that current processes identify all eligible individuals.)
  5. Facilitate pre-test genetics education and request of genetic testing.
  6. Facilitate cascade genetic testing.
  7. Collect targeted family history to determine genetic test eligibility.
  8. Return negative genetic test results to patients with chatbot.

Researchers

  1. Facilitate clinician scientists’ research around hereditary diseases.
  2. Automate screening family health history for other common, inherited conditions.
  3. Population Analytics
    1. Identify individuals who meet National Comprehensive Cancer Center (NCCN) criteria for hereditary cancer genetic testing enterprise-wide. Characterize the cohort.
    2. Identify individuals who meet NCCN criteria for genetic testing that are part of a pre-identified cohort (i.e., validate that current processes identify all eligible individuals.)
  4. Facilitate pre-test genetics education and request of genetic testing.
  5. Facilitate cascade genetic testing.
  6. Collect targeted family history to determine genetic test eligibility.
  7. Return negative genetic test results to patients with GARDE-Chat chatbot.

GARDE population health algorithms and GARDE-Chat chatbots have been tested extensively together and pair well. Chatbots created with GARDE-Chat can be used independently to evaluate non-genetics/cancer-related, scalable patient outreach, education, and healthcare access (e.g. we evaluated the effectiveness of the chatbot to offer COVID-19 test kits in federally qualified health centers (FQHC)).

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